Nurse seeking EB-2 with national interest waiver based on proposed specialized nursing work in hyperbaric oxygen therapy and ICU care. AAO held petitioner lacks advanced degree and proposed endeavor lacks national importance because benefits would not extend beyond her employer and coworkers to impact the nursing field broadly.

Dental care entrepreneur seeking NIW to establish dental practice. Claimed national importance based on dental professional shortage and environmental benefits of practice. AAO affirmed denial, finding that serving individual patients lacks national importance; professional shortage alone insufficient under Dhanasar framework.

Dentist sought EB-2 advanced degree classification and NIW for dental support organization services. AAO affirmed denial because proposed endeavor lacked national importance; evidence showed only local clinic impact, not broader field or economic implications required by Dhanasar.

A nutritionist employed by a state health department on federally funded WIC programs sought a national interest waiver. The AAO found her proposed work lacked national importance because it affected only direct clients, did not advance the nutrition field broadly, and showed no substantial economic effects, dismissing the appeal under Dhanasar's first prong.