An epigenetics and oncology researcher filed I-140 for extraordinary ability. He satisfied three initial criteria including original contributions of major significance. However, AAO reversed on final merits, finding productive career but insufficient sustained acclaim or evidence of very top of field status.

Biomedical researcher seeking EB-1A extraordinary ability met three criteria: judging, scholarly articles, and original contributions. Final merits determination found petitioner demonstrated sustained national acclaim and recognition in field, achieving level of expertise placing them among very top of field. Appeal sustained.

Research chemist sought EB-1A extraordinary ability classification. AAO found three criteria met but concluded final merits analysis demonstrated lack of sustained international acclaim or placement among small percentage at field top, dismissing appeal.

Researcher in gastroenterology sought EB-1A extraordinary ability. Director initially found only two criteria met, but AAO considered three criteria in final merits determination. AAO found petitioner failed all analyzed criteria and did not demonstrate sustained national or international acclaim required for classification.