An advanced degree professional sought national interest waiver for HVAC consulting. The AAO dismissed the appeal because the petitioner materially changed the proposed endeavor between initial filing and RFE response, preventing determination of well-positioned status under Dhanasar.

Cryptography researcher pursuing PhD seeks EB-2 advanced degree and NIW for research developing secure communication and privacy tools. AAO found proposed endeavor has substantial merit and national importance. However, petitioner lacks documented postdoctoral position or specific employment commitment, failing to establish he is well-positioned to advance the work.

Laboratory supervisor sought EB-2 with national interest waiver to conduct immunological research for drug development. AAO held petitioner not well-positioned to advance proposed endeavor; research publications and praise insufficient without concrete evidence of past success or funded future projects.

Physical therapist and entrepreneur sought EB-2 with national interest waiver to establish her own practice providing wellness services. AAO affirmed denial, finding her proposed endeavor lacked the national importance required under Dhanasar's first prong, as it had only local economic implications without broader field impact.