A family nurse practitioner seeks EB-2 advanced degree classification and NIW. Service center approved underlying EB-2 eligibility but denied NIW. AAO affirmed, finding petitioner's proposed primary care practice using telemedicine lacked national importance; evidence showed only individual patient benefit, not broader healthcare industry impact.

A nurse with advanced degree sought EB-2 classification and NIW. AAO affirmed denial, finding the proposed nursing work lacks national importance and does not impact the field broadly. Substantial merit was found but national importance was not established.

Biomedical scientist sought EB-2 with national interest waiver for genetic research on medical conditions. AAO found petitioner failed to establish advanced degree eligibility due to translation deficiencies and did not demonstrate national importance of proposed endeavor, lacking specific prospective impact evidence.

A home health services company owner sought EB-2 NIW classification as an advanced degree professional. The petitioner proposed operating a home health company aligned with federal healthcare initiatives. The AAO held that substantial merit in the field does not establish national importance; the specific endeavor must demonstrate broader implications or meaningful industry impact beyond serving prospective patients.