A chemist working for a pharmaceutical company claimed four criteria for extraordinary ability. The AAO affirmed the director's finding on judging and scholarly articles but rejected original contributions, finding employer statements about trade secrets and potential drug discoveries lacked evidence of major field impact.

A cybersecurity interaction designer sought EB-1A extraordinary ability classification. He claimed original contributions and other criteria. The AAO found he met only two criteria (leading role and high salary), falling short of the three required. His design work lacked demonstrated major significance beyond employer products, and he failed to establish sustained acclaim for the classification.

A nephrologist and kidney transplant specialist claimed extraordinary ability based on awards, association memberships, and published material. The AAO dismissed the appeal, finding no nationally or internationally recognized awards, memberships not requiring outstanding achievements, and publications not meeting the criterion of material about the petitioner.

Biostatistician claimed five EB-1A criteria. AAO dismissed because petitioner failed to establish lesser nationally or internationally recognized awards, and other criteria claimed on appeal were insufficient to meet extraordinary ability standard.