Immunology and food allergy researcher petitioner met two of three required initial criteria (judging and scholarly articles). AAO dismissed appeal, finding petitioner failed original contributions criterion; highly-cited publications alone insufficient without evidence of major field significance and lacking national or international acclaim.

A chemist working for a pharmaceutical company claimed four criteria for extraordinary ability. The AAO affirmed the director's finding on judging and scholarly articles but rejected original contributions, finding employer statements about trade secrets and potential drug discoveries lacked evidence of major field impact.

An honorary research professor in classical studies claimed seven evidentiary criteria for extraordinary ability. The service center accepted judging and scholarly articles. The AAO dismissed the appeal, finding the contested awards, membership, contributions and leading-role criteria unmet, so the three-criterion threshold failed and final merits were not reached.

Self-petitioner computational research scientist sought EB-1A classification in sciences. AAO found awards, judging, and original contributions criteria not met. Published material and membership claims abandoned or not analyzed. Petitioner failed three-criterion threshold; appeal dismissed.