Neuroscience researcher with Ph.D. seeks EB-2 self-petition with NIW for research on Alzheimer's and ataxia mechanisms using stem cells. AAO found all three Dhanasar prongs met: research has national importance with broader implications, petitioner well-positioned with advanced degree and track record, and waiver benefits U.S. given urgent medical need.

An entomology professor with a Ph.D. in medical entomology seeks an EB-2 national interest waiver for research on German cockroach insecticide resistance. AAO held the proposed endeavor lacks the specific detail, novelty, and documented potential for broad impact required to establish national importance under Dhanasar's first prong.

Pediatrician with foreign medical degree equivalent to U.S. first professional degree seeking EB-2 NIW. Proposed pediatric practice in Florida hospital, claiming lower disease treatment costs and reduced intensive care admissions. AAO found endeavor lacks demonstrated national importance; benefits limited to individual patients without broader healthcare industry implications.

Financial and investment analyst seeking EB-2 NIW claimed expertise in financial consulting. AAO held petitioner met underlying EB-2 but failed first Dhanasar prong; proposed business providing budgeting and forecasting services lacks national importance and broader field implications required.