Dentist qualified as EB-2 advanced degree professional but sought national interest waiver. AAO dismissed appeal, finding her proposed endeavor to practice dentistry lacked national importance; individual dental practice benefits patients and employer but lacks broader national prospective impact.

Financial manager with advanced degree sought NIW for employment in banking sector with proposed use of blockchain and AI technologies. AAO found substantial merit in the field but concluded the petitioner failed to demonstrate national importance of her specific endeavor, lacking evidence of broader industry impact, employment potential, or substantial economic effects.

A bioengineer and prosthetics researcher sought EB-2 classification with a national interest waiver. The AAO dismissed the appeal, finding she failed to establish a U.S. bachelor's or advanced degree equivalent and, even under exceptional ability, did not meet three evidentiary criteria. The proposed endeavor lacked specific evidence of national importance.

A hemodialysis nurse sought EB-2 classification with a national interest waiver for her proposed mobile dialysis service company. The AAO affirmed denial, finding the endeavor showed substantial merit addressing kidney disease but lacked the national importance required under Dhanasar because it would not impact the field broadly or generate substantial economic effects beyond serving her own patients.