A biomedical scientist and clinical pathology technician sought EB-2 with national interest waiver. The AAO dismissed the appeal, holding that the proposed biomedical company's services and training would not extend beyond individual clients to have national importance or broader field impact.

A postdoctoral researcher in metabolic diseases sought an EB-2 national interest waiver. She satisfied the first prong (substantial merit and national importance) but failed the second: she lacked a clear plan, institutional commitment, or funding evidence to demonstrate she was well-positioned to advance her work, so the appeal was dismissed.

A physician-researcher pursuing a Ph.D. in biomedical sciences seeks NIW for research on breast cancer biomarkers and early detection. The petitioner claimed three Dhanasar prongs. The AAO sustained the appeal, finding the proposed research has substantial merit and national importance, the petitioner is well-positioned to advance it given his medical degree and publication record, and waiving job offer requirements would benefit the United States.

Dentist with advanced degree sought EB-2 NIW for oral surgery and instruction work. AAO held the endeavor lacks national importance; while instructional work has substantial merit, it does not extend beyond individual trainees to impact dentistry field, public health, or the economy.