A home health services company owner sought EB-2 NIW classification as an advanced degree professional. The petitioner proposed operating a home health company aligned with federal healthcare initiatives. The AAO held that substantial merit in the field does not establish national importance; the specific endeavor must demonstrate broader implications or meaningful industry impact beyond serving prospective patients.

Physiotherapist with advanced degree sought EB-2 classification and national interest waiver to establish health and wellness clinic. AAO dismissed appeal, finding petitioner eligible for underlying EB-2 but failed to establish national importance required for waiver under Dhanasar's first prong.

A hemodialysis nurse sought EB-2 classification with a national interest waiver for her proposed mobile dialysis service company. The AAO affirmed denial, finding the endeavor showed substantial merit addressing kidney disease but lacked the national importance required under Dhanasar because it would not impact the field broadly or generate substantial economic effects beyond serving her own patients.

Financial manager with advanced degree sought NIW for employment in banking sector with proposed use of blockchain and AI technologies. AAO found substantial merit in the field but concluded the petitioner failed to demonstrate national importance of her specific endeavor, lacking evidence of broader industry impact, employment potential, or substantial economic effects.