Physiotherapist with advanced degree sought EB-2 classification and national interest waiver to establish health and wellness clinic. AAO dismissed appeal, finding petitioner eligible for underlying EB-2 but failed to establish national importance required for waiver under Dhanasar's first prong.

Nurse with advanced degree initially proposing primary care work in underserved Florida areas, later proposing occupational health consulting company. AAO held both endeavors lack national importance under Dhanasar; healthcare field importance alone insufficient for specific endeavor-level impact.

Nurse proposing clinical safety audit implementation claims national interest waiver. AAO agreed proposal has substantial merit but found no national importance: letters lacked specific evidence that the endeavor offers broader healthcare field implications or substantial positive national economic effects.

A hemodialysis nurse sought EB-2 classification with a national interest waiver for her proposed mobile dialysis service company. The AAO affirmed denial, finding the endeavor showed substantial merit addressing kidney disease but lacked the national importance required under Dhanasar because it would not impact the field broadly or generate substantial economic effects beyond serving her own patients.