Cell biologist sought EB-1A extraordinary ability in sciences. Petitioner met initial three criteria: judging, original contributions, and scholarly articles. On final merits analysis, AAO found petitioner's accomplishments not commensurate with sustained national or international acclaim required. Appeal dismissed.

Postdoctoral molecular biology researcher seeks EB-1A extraordinary ability. Met judging and scholarly articles criteria but failed original contributions criterion. AAO held that citations and journal prestige alone do not demonstrate contributions of major significance in the field.

Postdoctoral researcher in sciences claimed extraordinary ability under awards, membership, and published material criteria. AAO found petitioner met one criterion (membership in Sigma Xi and ASBMB) but failed to meet required threshold of at least three criteria. Evidence showed postdoctoral talent but insufficient to demonstrate sustained national or international acclaim at very top of field.

Molecular biologist in computational biology claimed three criteria. AAO found petitioner met judging and scholarly articles criteria but not original contributions of major significance, as letters lacked evidence of realized or implemented contributions, and citations alone without field context do not establish major significance. With only two criteria met, appeal was dismissed.