Legal analyst with advanced degree sought national interest waiver for self-employment. AAO affirmed denial under Dhanasar because proposed endeavor lacked national importance; petitioner's business would serve only local clients without broader field implications or substantial economic effects beyond her own enterprise.

Nurse seeking EB-2 with national interest waiver based on proposed specialized nursing work in hyperbaric oxygen therapy and ICU care. AAO held petitioner lacks advanced degree and proposed endeavor lacks national importance because benefits would not extend beyond her employer and coworkers to impact the nursing field broadly.

An entrepreneur seeks NIW as EB-2 advanced degree professional to establish a company offering reputation, positioning, and brand-building consultancy to corporations. The AAO dismissed the appeal because the petitioner failed to show the endeavor has national importance, as it lacks broader implications extending beyond the company's clients to the relevant fields.

A marketing consultant seeks NIW status to operate a digital and traditional marketing agency serving small and medium-sized businesses. The AAO acknowledged substantial merit but found the business plan insufficient to demonstrate national importance because benefits would not extend beyond individual client companies to impact the marketing industry.